מחקר: Longevity (32)
32 מאמרים בנושא Longevity, מאונדקסים על ידי PF-Atlas מ-PubMed וכתבי עת עולמיים.
- Therapeutic reversal of cellular senescence: A systematic review of senolytics, senomorphics and anti-ageing therapies in human clinical trials. · British journal of clinical pharmacology · 2026
- Pharmacological targeting of the senescence-associated secretory phenotype in atherosclerosis: therapeutic potential of senolytics and senomorphics. · Naunyn-Schmiedeberg's archives of pharmacology · 2026
- Pseudomonas aeruginosa infection causes lysosomal dysfunction in the cystic fibrosis bronchial epithelium. · Infection and immunity · 2026
- Advancements in longevity pharmacology research - are we finally seeing clinical progression? · Expert opinion on investigational drugs · 2026
- Inflammaging: Experimental Insights and Translational Advances. · European journal of immunology · 2026
- Low-Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle-Aged and Older Adults: Study Protocol for a Triple-Blind, Randomised, Placebo-Controlled Trial. · Basic & clinical pharmacology & toxicology · 2026
- Lung mTOR activation leads to lung fibrosis or emphysema via senescence of specific lung cells. · Scientific reports · 2026
- Short-Term Rapamycin Mitigates the Senescence of Ovaries and Somatic Stem Cells in Multiple Organs in Reproductively Aged Mice. · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
- Aged circulating CD8 T cells and their secreted factors drive cognitive decline. · Immunity · 2026
- Blood as the mirror and modulator of aging: mechanistic insights and rejuvenation strategies. · Experimental & molecular medicine · 2026
- Immunotherapy and senolytics in head and neck squamous cell carcinoma: phase 2 trial results. · Nature medicine · 2025
- Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease. · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
- Human Umbilical Cord Blood Plasma-Derived Exosomal miR-410-3p Alleviates Liver Injury by Regulating the Mitochondria-Mediated Antiapoptotic Signaling. · MedComm · 2025
- Protocol for a pilot clinical trial of the senolytic drug combination Dasatinib Plus Quercetin to mitigate age-related health and cognitive decline in mental disorders. · F1000Research · 2024
- Polyphenols and Diets as Current and Potential Nutrition Senotherapeutics in Alzheimer's Disease: Findings from Clinical Trials. · Journal of Alzheimer's disease : JAD · 2024
- Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results. · Nature medicine · 2024
- Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma. · Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
- Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial. · Nature medicine · 2023
- Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types. · Nature aging · 2023
- Senolytic Therapy to Modulate the Progression of Alzheimer's Disease : A Pilot Clinical Trial. · The journal of prevention of Alzheimer's disease · 2022
- Circulating microRNA Signature Associated to Interstitial Lung Abnormalities in Respiratory Asymptomatic Subjects. · Cells · 2020
- Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. · EBioMedicine · 2019
- Activation of the mTORC1/PGC-1 axis promotes mitochondrial biogenesis and induces cellular senescence in the lung epithelium. · American journal of physiology. Lung cellular and molecular physiology · 2019
- Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases. · American journal of respiratory and critical care medicine · 2019
- Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging. · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
- Adipose Tissue Senescence and Inflammation in Aging is Reversed by the Young Milieu. · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
- PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses. · Inflammation and regeneration · 2018
- Therapeutic potential of systemic brain rejuvenation strategies for neurodegenerative disease. · F1000Research · 2017
- Mammalian Target of Rapamycin: A Target for Diseases and Aging. · Annals of the American Thoracic Society · 2016
- Mammalian Target of Rapamycin Inhibition With Rapamycin Mitigates Radiation-Induced Pulmonary Fibrosis in a Murine Model. · International journal of radiation oncology, biology, physics · 2016
- mTORC1 activation decreases autophagy in aging and idiopathic pulmonary fibrosis and contributes to apoptosis resistance in IPF fibroblasts. · Aging cell · 2016
- Aging and brain rejuvenation as systemic events. · Journal of neurochemistry · 2015
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