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Исследования: Senolytics (19)
19 публикаций в теме «Senolytics», проиндексированных PF-Atlas из PubMed и мировых журналов.
- Beyond scarring: a next-generation vision for pulmonary fibrosis management. · Molecular biology reports · 2026
- Beyond attenuation: a translational review of curative-intent pharmacological targets in idiopathic pulmonary fibrosis. · Frontiers in medicine · 2026
- Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach. · Frontiers in immunology · 2025
- Senolytic Therapy Enabled by Senescent Cell-Sensitive Biomimetic Melanin Nano-Senolytics. · Advanced healthcare materials · 2024
- Researching New Drug Combinations with Senolytic Activity Using Senescent Human Lung Fibroblasts MRC-5 Cell Line. · Pharmaceuticals (Basel, Switzerland) · 2024
- Addition of Polyphenols to Drugs: The Potential of Controlling "Inflammaging" and Fibrosis in Human Senescent Lung Fibroblasts In Vitro. · International journal of molecular sciences · 2024
- Potential Clinical Implications of Senotherapies for Cardiovascular Disease. · Circulation journal : official journal of the Japanese Circulation Society · 2024
- Senolytic drugs dasatinib and quercetin in idiopathic pulmonary fibrosis: a first-in-human, open-label, pilot study · The Lancet Respiratory Medicine · 2023
- Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability. · EBioMedicine · 2023
- Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans. · EBioMedicine · 2022
- Strategies for late phase preclinical and early clinical trials of senolytics. · Mechanisms of ageing and development · 2021
- Prospective Selective Mechanism of Emerging Senolytic Agents Derived from Flavonoids. · Journal of agricultural and food chemistry · 2021
- Cellular Senescence in Idiopathic Pulmonary Fibrosis. · Current molecular biology reports · 2021
- Senolytic drugs: from discovery to translation. · Journal of internal medicine · 2020
- Emerging use of senolytics and senomorphics against aging and chronic diseases. · Medicinal research reviews · 2020
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease. · EBioMedicine · 2019
- Hsp90 inhibitors as senolytic drugs to extend healthy aging. · Cell cycle (Georgetown, Tex.) · 2018
- Cellular senescence mediates fibrotic pulmonary disease. · Nature communications · 2017
- Inhibition of Bcl-2/xl With ABT-263 Selectively Kills Senescent Type II Pneumocytes and Reverses Persistent Pulmonary Fibrosis Induced by Ionizing Radiation in Mice. · International journal of radiation oncology, biology, physics · 2017
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